Is it possible to specify stereochemical configuration when constructing a query using the sketcher?
The 2D representations of structures in the database only contain information concerning connectivity of atoms, no stereochemical information is given in these diagrams. As a result, it is not possible to sketch a query in terms of ‘up and down’ or ‘dark filled/dashed line’ bond representation. Absolute stereochemistry is included in the CSD but only when the information is provided by the author in the original publication.