Is SYBR® Safe DNA gel stain compatible with the same applications as ethidium bromide?
Here is an instrument (MaestroGen UltraBright LED transilluminator) that can be used for both EtBr and SyBr safe dyes. The sensitivity for SyBr safe is great. For EtBr, the sensitivity is very good compared with 365 nm UV, a little bit weaker compared with 302 nm but enough. The following links are about the products.
SYBR® Safe DNA gel stain is compatible with all downstream applications we have tested so far, including excising PCR products from gels, gel purification, Gateway® cloning, TOPO® cloning, and restriction enzyme cloning. If you have a unique application that works with SYBR® Safe DNA gel stain, send us the details at techsupport@invitrogen.com.