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Ive read that only fresh Salvia divinorum leaves can be used, and I have also read that the active compound is unstable. Are these points true?

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Ive read that only fresh Salvia divinorum leaves can be used, and I have also read that the active compound is unstable. Are these points true?

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The idea that only fresh leaves can be used probably comes from the fact that traditionally the Mazatec Indians only used fresh leaves to make their infusions. The Mazatecs were apparently unaware that the plant could be dried and smoked. Interestingly, they also may consider Salvia divinorum to be a fairly “weak” plant–not surprising considering the way they consume it, which is one of the least effective methods. Not only can dried leaves be smoked, but dried leaves can also be reconstituted with water and used as a quid. A “dose” in this manner may be about 2 to 10 grams of leaf material, before it has been reconstituted with water (soak the leaves for 5-10 minutes to reconstitute them). Soaking dry leaves in water will increase their mass by 8-12 times. The idea that the active compound is unstable comes from an early investigation by Albert Hofmann. He took some material preserved in alcohol from Mexico back to Switzerland, to study it in his lab. Apparently this material was ina

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