Lipids were measured, but are there data for LDL particle size and number?
No. At the initiation of the study, LDL particle size and number were not routinely measured in clinical practice. Lipid parameters measured included triglycerides, HDL cholesterol, and direct LDL cholesterol. Back to the Top 23. Almost half of the patients had serious side effects. Serious adverse events were included in the endpoint analysis and were defined as: fatal, life-threatening, required inpatient hospitalisation, or occurred while in hospital and prolonged hospital stay and resulted in persistent or significant disability or incapacity. Overall, pioglitazone had numerically (but not significantly) fewer serious adverse events, endpoint events, and non-endpoint events than the placebo group.
