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My molecule has a disulfide, not a sulfhydryl functional group. Will that still conjugate using the eFluor® Nanocrystal Sulfhydryl-Reactive kit?

April 26, 2017conjugate disulfide Functional group kit molecule nanocrystal sulfhydryl sulfhydryl-reactive

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My molecule has a disulfide, not a sulfhydryl functional group. Will that still conjugate using the eFluor® Nanocrystal Sulfhydryl-Reactive kit?

1 Answer

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Yes, free sulfhydryl groups as well as disulfide bonds and cysteine groups may be used to conjugate to the Sulfhydryl-Reactive eFluor® Nanocrystal Conjugation Kit.