My patient is taking Clonazepam. Why don’t I see a positive result on the Point-of-Care Test?
The Point-of-Care tests have limited reactivity with some benzodiazepines. Currently, the benzos that react poorly or DO NOT react include: Bromazepam, Chlordiazepoxide, Clonazepam, Delorazepam, Estazolam, Lorazepam, Midozelam, and Triazelam. In order to get definitive results, the physician should request a “Confirm All Negative” Screen from Millennium Laboratories. In many cases the presence of the drug is confirmed by its metabolites. We measure those metabolites: Nordiazepam, Oxazepam, and Temazepam.
