The levels of oxymorphone are higher than oxycodone. Is my patient abusing Opana?
Not necessarily. Clinical trials indicate that the ratio of oxymorphone to oxycodone can vary from 0-184 percent and there is no direct correlation between the dose and the resulting ratio. Oxymorphone also has a slightly longer retention time in the urine than oxycodone meaning that oxymorphone may still be detectable following complete excretion of any oxycodone.