What are causes of IVF failure?
Success rate of IVF depends upon the age, general condition of female partner, cause of infertility in couple, response to fertility drugs, number of eggs retrieved and fertilized, number of embryos transferred, condition of uterus, laboratory standard and experience of center. a) Maternal age: Success rate of IVF decreases with increasing maternal age as number of eggs produced and their fertilization rate decreases with increasing age. Success rate of IVF is 53% for women in age group of 25 to 35 years, where as it is 18% for woman in the age group of 40 to 44 years. b) Cause of infertility: This is another important factor deciding the outcome of IVF cycle. Highest success rates are found in patients having tubal damage with good uterine cavity and lowest among those with male factor infertility. Infection of uterus causes adhesions or scarring in uterine cavity or decreased endometrial thickness that can cause implantation failure. Also general ill health, debility and systemic dis
