What are Gastrinomas?
Gastrinomas are tumors characterized by secretions of large amounts of gastrin, a hormone that increases the amount of acid released by the stomach. Gastrinomas are most commonly associated with Zollinger-Ellison syndrome (ZES) (ZES), a rare gastroenterological disorder. This disorder is more commonly referred to as peptic ulcer disease and is also sometimes called gastrinoma because of its close association with gastrinomas. Gastrinomas most often occur in the duodenum and the pancreas, though they may also occur in the pituitary gland and the hyperfunction of the parathyroid gland. About 66% of gastrinomas are malignant, often spreading to the patient’s liver. In addition, due to the increased production of acids by the gastrinomas, patients with ZES develop large numbers of severe ulcers. These are mostly located in the stomach or the duodenum. In the early stages of ZES disease, peptic ulcers are the most typical symptom. After ZES has become more established in the body, these ulc
