What are normal endogenous androgen and estrogen levels?
The normal endogenous androgen range in a male is 300-1100 nanograms per deciliter. Estrogen is generally below 50 picograms per milliliter. The normal endogenous androgen range in a female is 10-100 nanograms per deciliter. (within this range lower numbers are not necessarily considered better; remember, free-circulating androgens cannot bind to receptors very well, and therefore cannot cause much harm, if an androgen blocker is being used). There are dramatic cyclic and individual variations of estrogen (estradiol + estrone) in females, with 100-400 picograms per milliliter being the most usual, with 25-700 being possible depending on the individual. 400 is considered a nominal “mid-peak” (ovulation) level. 200-250 is considered a reasonable target for exogenous estrogen treatment. Note that only natural estrogens can be meaningfully measured, so it you take any estrogen besides estradiol valerate, estradiol cypionate, or estradiol, you will not be able to accurately judge the result