What are Tenofovir (TDF) and Emtricitabine (FTC)?
TDF and FTC are antiretroviral medicines that come together in a single pill. It is used, in combination with other antiretrovirals, to treat people who have HIV infection. It prevents HIV from growing and spreading in the body. Why do we think it is safe? TDF/FTC is widely used for treatment in the United States, Europe, and in some African countries but not yet in Botswana. For treatment of HIV infection, it is taken once a day, doesn’t cause many side effects, and is very slow to develop resistance. It has been tested in a few people without HIV infection for a short period of time and it appeared to be safe for them. How will the study be done? We will invite 1200 men and women in Francistown and Gaborone to join the study. They must be citizens of Botswana, 18-29 years old, already sexually active, and healthy. The study will be carefully explained and those people who fully understand the study will be asked to give their consent to be in the study. We will help everyone in the s
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