What are the chances I will need my child’s UCB product?
Most transplant physicians discourage using an autologous cord blood unit in the cases of childhood leukemia and other disorders as the stem cells in the unit may also have a genetic defect or predisposition to disease. Also, cells from another person might better fight the leukemia than the child’s own when used for a transplant. Some of the products collected for private storage are used for allogeneic sibling transplants. Cord blood transplants in children with malignant or non-malignant disease from an HLA-matched or one antigen disparate donor demonstrate a 10-fold lower incidence of graft-versus-host disease than that seen after transplantation with an HLA-matched bone marrow obtained from a sibling.2 Calculations vary among statisticians and organizations regarding the chances of using a stored cord blood product. The Center for International Blood and Marrow Transplant Research (CIBMTR) presented data at the 2005 American Society for Hematology meeting describing the overall li
Most transplant physicians discourage using an autologous cord blood unit in the cases of childhood leukemia and other disorders as the stem cells in the unit may also have a genetic defect or predisposition to disease. Also, cells from another person might better fight the leukemia than the child’s own when used for a transplant. Some of the products collected for private storage are used for allogeneic sibling transplants. Cord blood transplants in children with malignant or non-malignant disease from an HLA-matched or one antigen disparate donor demonstrate a 10-fold lower incidence of graft-versus-host disease than that seen after transplantation with an HLA-matched bone marrow obtained from a sibling.2 Calculations vary among statisticians and organizations regarding the chances of using a stored cord blood product. The Center for International Blood and Marrow Transplant Research (CIBMTR) presented data at the 2005 American Society for Hematology meeting describing the overall li
