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What causes long-term muscle cramps and spasms long after transplant?

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What causes long-term muscle cramps and spasms long after transplant?

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Patients with active chronic GVHD affecting the muscles can often have cramping and spasms as a result of the disease process. Medications to treat GVHD may also cause leg cramps. Cramps may persist for many years after GVHD is resolved, and cramps can be a problem for patients who have never had GVHD. Little is know about the cause of this symptom.

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