What Causes Osteoarthritis Pain in a Joint?
What Causes Osteoarthritis Pain in a Joint?Osteoarthritis pain is clearly the most common and significant symptom associated with the disease. Because articular cartilage has no blood supply and no nerve endings what causes the pain? Answer: Osteoarthritis pain likely comes from other structures within the affected joint. For example, structures that change with osteoarthritis include: Subchondral bone – This is the layer of bone just below the cartilage. When someone has osteoarthritis, there is increased blood flow and other changes that develop in the subchondral layer — subchondral sclerosis (increased bone density), subchondral cysts (fluid-filled sacs which extrude from the joint), and increased pressure within the bone —