What causes PSA levels to increase after prostate removal due to benign prostatic hyperplasia?
Prostate surgery is one treatment for noncancerous prostate gland enlargement (benign prostatic hyperplasia, or BPH). The surgery reduces the amount of prostate tissue around your urethra by removing some — but not all — of your prostate. Following surgery, it’s possible for the prostate gland to regrow, which can cause an increase in prostate-specific antigen (PSA) levels. You may also experience elevated PSA levels if not enough of your prostate is removed. In addition, elevated PSA levels can indicate: Inflammation of the prostate (prostatitis). Infection or inflammation of the prostate gland can cause your PSA levels to increase. Once prostatitis is treated with antibiotics, PSA levels should return to normal. Recurrent BPH. Despite prostate surgery, BPH can recur and cause your PSA levels to increase. Some men may need a second surgery after a number of years. Prostate cancer. Prostate cancer cells — in your prostate or in other parts of your body — may be secreting PSA. Recent ej