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What combination of drug and alcohol has a SERIOUS POTENTIAL FOR OVERDOSE?

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What combination of drug and alcohol has a SERIOUS POTENTIAL FOR OVERDOSE?

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The most dangerous is barbiturates and alcohol. Why: Drug tolerance occurs quickly with barbiturates – like Seconal. The more one takes the more one needs. The levels build up. Then the potential for death occurs where one or two drinks, because the level of sedation triggers an unrecoverable unconsciousness and CNS death.

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