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What does hydrogen ions, lactic acid and carbon dioxide have to do with neuromuscular fatigue?

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What does hydrogen ions, lactic acid and carbon dioxide have to do with neuromuscular fatigue?

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When the muscles work very hard, they produce carbon dioxide, which is released on to the bloodstream. However, if the muscles work extremely hard, the carbon dioxide they produce are eventually utilized through glucose creating lactate. Hydrogen ions combine with lactate producing lactic acid.

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