What happens in the brain and nervous system to cause migraine symptoms?
There is increasing evidence that migraine is a neurobiological disorder, meaning that it begins or originates in the brain. Presumably, there is something that turns the migraine switch on. Or alternatively, a mechanism that prevents us all from having headaches somehow fails. In fact, it may be a combination of both — that is, something that essentially switches the migraine on, but also the failure of mechanisms that suppress that. But it does appear that deep within the brain, within what we call the brainstem, are messaging centers where an attack appears to originate.
