What is Cytogenetic Microarray testing?
This testing is an advancement in cytogenetic technology that allows us to detect cytogenetic imbalances that are smaller than what can be detected through routine chromosome analysis. This test will be an invaluable tool for diagnosis in patients with a variety of indications when a chromosomal imbalance is suspected, but cannot be detected through traditional chromosome analysis. Cincinnati Children’s Cytogenetics Laboratory offers testing that will detect the loss (deletion) or gain (duplication) of chromosomal regions: • MICROARRAY SNP (MA-SNP) testing uses BeadChip technology to examine approximately 610,000 separate chromosomal regions. We use the Infinium® Assay with the Illumina® HD Human610-quad BeadChip platform in our SNP (Single Nucleotide Polymorphism) based platform. This array is used to detect chromosomal imbalances throughout the genome. The resolution of this array can detect imbalances that are as small as 80-100 Kb with gaps in coverage of 1 Megabase or less. This a
