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What is Hypereosinophilic Syndrome (HES) and/or Chronic Eosinophilic Leukemia (CEL)?

April 26, 2017cel chronic eosinophilic hypereosinophilic leukemia SYNDROME

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What is Hypereosinophilic Syndrome (HES) and/or Chronic Eosinophilic Leukemia (CEL)?

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Hypereosinophilic syndrome (HES) is a blood disorder characterized by unexplained, higher than normal levels of eosinophils, a type of white blood cell, and evidence of organ dysfunction due to eosinophilic tissue infiltration. In some cases, it can additionally be characterized by elevated levels of immature mast cells in the bone marrow and mast cell products in the blood. When associated with chromosomal abnormalities, the disease is then called chronic eosinophilic leukemia (CEL).