What is Of Mice and Men means?
The full quote is “The best laid plans of mice and men oft go awry”. The quote is adapted from a line in the poem “To a Mouse” by Scottish poet Robert Burns: “The best laid schemes o’ mice an’ men Gang aft agley” The phrase means that the best plans can’t always be followed due to unforeseen complications or events that change the course of one’s path through life. Basically it is a poetic way of saying “sh** happens.