What is RapidFire®?
RapidFire® is a technology that allows label-free, high-throughput measurement of biologically relevant reactions. The technology resulted from a need to develop assays for otherwise intractable targets, such as those that are not amenable to screening using traditional methods such as fluorescence or radiolabels. By utilizing mass spectrometry to quantitate conversion of unlabeled substrate to product, assays are developed that can directly measure attenuation of reactions using libraries of lead compounds. RapidFire® technology has allowed the development of assays for a wide range of targets that have otherwise proven very difficult to study. These include triglycerides, lipids, fatty acids, prostaglandins, steroids, co-enzyme A derivatives, neurotransmitters, antifungals and antiinfectives. RapidFire® is a “stand-alone” platform, which is easy to integrate due to the standard plate format and preparation protocols used.
