What is the difference between a Model and Strain in the AMDCC web portal?
Although investigators use the words Model and Strain interchangeble, the AMDCC web portal defines them as separate terms because one strain could be associated with one or more models. Therefore, we must separate the concepts in order to store the appropriate data in the system. Models are defined as combination of species, animal strain, diabetes type and complication type. The models could also have specific diabetes and complication induction protocols. A strain, on the other hand, is the actual animal being assayed and is defined by the genetic makeup, construction method, partental strains, and status.