What is the dosing schedule for Twinrix®?
The recommended standard primary course of vaccination with Twinrix® consists of three doses. The first dose is administered at the elected date, the second one month later and the third dose six months after the first dose (0, 1, 6 month schedule).2 The alternate dosing schedule, for children and adolescents only (ages 1 to 15 years), consists of two doses of Twinrix®. The first dose is administered at the elected date and the second between six and twelve months after the first dose. The alternate schedule should be used where completion of the two-dose vaccination course can be assured, such as school-based vaccination programs. A rapid schedule of three injections given at 0, 7 and 21 days may be an option when travel is anticipated within one month after initiating the vaccination course and where insufficient time is available for the standard schedule.
