What is the function of the drug histamine?
Sexual response Research has shown that histamine is released as part of the human orgasm from mast cells in the genitals. If this response is lacking this may be a sign of histapenia (histamine deficiency). In such cases, a doctor may prescribe diet supplements with folic acid and niacin (which used in conjunction can increase blood histamine levels and histamine release), or L-histidine. Schizophrenia It has been found that about half the patients classified as suffering from schizophrenia have low histamine levels in the blood.[4] This may be because of antipsychotics that have unwanted effect on histamine, such as quetiapine. Although, in these cases, as histamine levels were increased, their health improved. Sleep regulation Histamine is released as a neurotransmitter. The cell bodies of neurons which release histamine are found in the posterior hypothalamus, in various tuberomammillary nuclei. From here, these histaminergic neurons project throughout the brain, to the cortex thro