What is the resolution of CytoSure cytogenetic arrays?
Syndrome Plus arrays: • a microarray slide containing two arrays, each with 105,000 spots • 200+ syndromes – on average, one probe every 3 kb, 33 probes/gene, including 5 kb of flanking region • 410 genes associated with autism, mental retardation (MR), heart diseases and eye diseases – on average, one probe every 3 kb, 33 probes/gene, including 5 kb of flanking region • extensive genome coverage, including subtelomeres – one probe every 40 kb. Chromosome X High Density arrays: • a microarray slide containing two arrays, each with 105,000 spots • higher resolution – one probe every 1.6 kb • gene-centric design – one probe every 500 bp for all known gene loci including 5kb of flanking region • targeting of genes, exons, miRNAs, rRNAs and snRNAs on X chromosome. Chromosome X exon specific arrays: • a microarray slide containing four arrays, each with 44,000 spots • one probe every 4 kb • exon-centric design – probe design biased towards expression regions • ideal for screening large numb
