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What is the solubility of SNAP-tag in insect and bacterial expression systems?

April 26, 2017bacterial expression insect snap-tag solubility SYSTEMS

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What is the solubility of SNAP-tag in insect and bacterial expression systems?

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Our finding is that SNAP-tag is neutral with regard to the solubility of fusion proteins. SNAP-tag on its own is expressed in a soluble form in bacteria and insect cells. Naturally, the addition of a fusion partner is likely to influence the solubility of the expressed fusion protein.