What is transmissible spongiform encephalopathies?
Transmissible spongiform encephalopathies (TSEs) are a group of fatal degenerative diseases that affect the central nervous system and can occur in humans and certain animal species. They are characterized by microscopic vacuoles and the deposition of amyloid (prion) protein in the gray matter of the brain which causes it to appear “spongy”. The most common TSE among humans is Creutzfeld-Jacob-Disease (CJD), which has a worldwide rate of approximately one case per million people each year. Bovine spongiform encephalopathy (BSE), commonly referred to as “mad cow disease” is a TSE that affects cattle. It is thought to be due to the feeding of rendered bovine meat and bone meal to young calves. More Information for Health Care Providers on Creutzfeld-Jacob-Disease (CJD).
