What makes TGC different from glucosamine taken orally?
When glucosamine is consumed orally, it goes through the gastrointestinal tract and liver first-pass, where it is rapidly metabolized, resulting in only a small proportion of glucosamine reaching the blood. This proportion of glucosamine is then circulated throughout the entire body, resulting in ultimately an even smaller proportion of glucosamine reaching joints where it is in fact needed the most. Also, oral consumption of glucosamine may result in gastrointestinal side effects.