What method should I use to amplify my ChIP samples?
Past and present NimbleGen ChIP-chip customers have had very good experiences working with the Sigma-Aldrich GenomePlex WGA2 Kit (#WGA2-50RXN). The WGA method seems to be easier and the quality of the amplified DNA is quite good. Many customers find that it is difficult to get LM-PCR to work well. For those that are just beginning ChIP-chip studies, we recommend the use of WGA.
