Apart from the fact that medical science is involved and also two doctors, Dr Frankenstein and Dr Jekyll, I can’t see parallels at all except for possibly the consequences of actions. One is about the building of the perfect man and the consequences of attempting that and the other explores the darker hidden side of human nature although what happened with Mr Hyde was not what was intended. I’m afraid I can’t give you any quotes because it is a while since I have read either book and my memory is not what it used to be.