What sort of patients are suitable candidates for treatment with anti-TNF antibody?
CD patients with active disease despite therapy with steroids; this is a prerequisite for enrollment in the studies. Those patients who may particularly be suitable for the anti-TNF therapy are those who cannot tolerate 6-mercaptopurine or in whom 6-mercaptopurine has not worked or have just been started on 6-mercaptopurine and a therapeutic effect is not expected for several months. IMPORTANT: the anti-TNF antibodies are only available as part of formal studies at present.
