What species of Mycobacteria test positive with T-SPOT.TB?
The T-SPOT.TB test produces positive results in all three TB-causing species of the Mycobacterium tuberculosis Complex; M. tuberculosis, M. bovis and M. africanum. The antigens used in the test, ESAT-6 and CFP10, are present in three other atypical or non-tuberculosis mycobacteria; M. marinum, M. szulgai and M. kansasii. The test may produce positive results in patients infected with these three mycobacteria. The antigens used in the test are not present in other non-tuberculosis mycobacteria.