What would the ideal concentration of NaOH be if I were to hydrolyse aspirin before using back titration to find its purity?
Chris Otter of Salters Advanced Chemistry replies This is a bit of a ‘how long is a piece of string’ one. It really depends on how many tablets are hydrolysed. One method, given in Chemistry in context, Laboratory manual and study guide by G. Hill and J. Holman, recommends 5 tablets hydrolysed in 25 cm3 of 1.0M NaOH. Of course the caustic solution needs to be standardised. The hydrolysed mixture is made up to 250 cm3 and a 25 cm3 aliquot titrated with 0.1M HCl. You should be able to calculate the numbers of moles involved and therefore determine appropriate concentrations and volumes.
Related Questions
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- What would the ideal concentration of NaOH be if I were to hydrolyse aspirin before using back titration to find its purity?
