Where can I obtain the GPCR-specific BLAST sequences needed to run with the Align GPCR option in the Edit Alignment step?
You can download the GPCR-specific BLAST sequences from the Schrödinger ftp site. The sequences are provided in a compressed tar file, which can be found at: ftp://ftp.schrodinger.com/support/hidden/gpcr/gpcr_blastdb.tar.gz If you are prompted, the username is anonymous and the password is your email address. You will need to type the pathname and file exactly as shown above, as the directories and contents are hidden.