Who should not take ACE inhibitors?
ACE inhibitors protect the kidneys of diabetics by slowing the progression of kidney failure. However, in patients with severe kidney failure these drugs may aggravate the condition and cause retention of potassium. However, under certain circumstance it may be beneficial in chronic renal failure, but is only used with caution, close supervision and specialist advice. Patients using ACE inhibitors should not take potassium-sparing drugs like certain diuretics, or potassium supplementation. ACE inhibitors must not be used during pregnancy or if planning to fall pregnant. It may cause birth defects and fetal death. Compelling contraindications • Pregnancy. • Hyperkaleamia high blood levels of potassium. • Bilateral renal artery stenosis narrowing of the arteries that supply the kidneys, on both sides. • Angio-oedema. Possible contraindications or limited value • Renal impairment patients with kidney disease may retain potassium. • Peripheral vascular disease. • Limited value as monothera
