Why does MRC-Holland occasionally change the exon numbering or gene name used in its product materials?
One gene may be known under various aliases. MRC-Holland has chosen to use only those gene names that have been officially approved by the HUGO Gene Nomenclature Committee. Any alternative names can be easily found by doing a search on www.genenames.org. A similar policy is applied to exon numbering. Although for most genes, exon numbering is relatively simple, there are also genes for which various numbering systems exist. Usually, these are genes for which as older (but factually incorrect) exon numbering had already become in widespread use, or genes which consists both of coding and noncoding exons or have rare transcript variants. MRC-Holland has chosen to use only the exon numbering system of National Center for Biotechnology Information (NCBI) in all its product materials. When NCBI changes its exon numbering, any product materials will also be changed at the moment that the product in question is updated. The changing of gene names and exon numbering in an inevitable consequenc
