Why Pomegranate Fruit Extract?
Topically, pomegranate extract is especially effective in protecting cells from free radical damage by inhibiting the formation harmful enzymes that cause cells to grow out of control. The ellagic acid, found within pomegranate extract is also thought to strengthen the cell membrane, making it less susceptible to free radical damage and preventing water loss. Such properties have important implications in terms of cancer prevention, as out-of-control cell division is a hallmark of cancer. Researchers at the University of Wisconsin, evaluated pomegranate’s anti-skin tumor effects by comparing topical application of pomegranate extract on neonatal mice against TPA-induced markers (12-0-tetradecanoylphorbol-13-acetate), a strong promoter of chemically induced skin cancer. Applying pomegranate extract onto the skin of neonatal mice 30 minutes prior to TPA application significantly inhibited TPA-mediated increases in skin edema and hyperplasia, they said.